We’re taught that fruit is good for you and a decent substitute for unhealthy foods, so this might come as a surprise. Sure, grapefruit is healthy, but it can be a real no-go if you’re taking medication. Grapefruit messes with how your body absorbs meds. It’s got compounds that mess with the enzymes that break down drugs. This can lead to higher concentrations of the drug in your bloodstream.

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If you’re on any medication, it’s best to chat with your doctor about whether grapefruit could be an issue. If it is, switching grapefruit for another citrus fruit probably won’t make a difference, unfortunately.

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